Human MET proto-oncogene, receptor tyrosine kinase
with merestinib
GtoP Target: MET proto-oncogene, receptor tyrosine kinase
Structure
Sequence
mhhhhhhmgdsdisspllqntvhidlsalnpelvqavqhvvigpsslivhfnevIgrghfgcVyhgtlldndgkkihcAvKslnritdigevsqfltEgiIMkdfshpnvlsllgiclrsegsplvvLPYMkhgdlrnfirnethnptvkdligfglqvakgmkyLaskkfvhrdlaarncmldekftvkVADFglardmydkeyysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfig
PDB Details
| PDB code | 4EEV |
| HET ID | A1401 |
| HET name | L1X |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 8.3 |
| Affinity type | pIC50 |
? Sequence length |
140 |
? Proportion of original chain length |
43.8% |
? Internal contacts |
3545 |
? External contacts |
373 |
? Contact ratio |
9.504022 |
Features
Residue Distances