Human B-Raf proto-oncogene, serine/threonine kinase
with BGB-283
GtoP Target: B-Raf proto-oncogene, serine/threonine kinase
Structure
Sequence
mkkghhhhhhgsrdssddweipdgqitvgqrIgsgsfgtVykgkwhgdvAvKmlnvtaptpqqlqafknEvgVLrktrhvnILlfmgystkpqlaIvTQwCegsslyhhlhasetkfemkklidiarqtargmdyLhaksIihrdlksnniFlhedntvkigDfglateksrwsgshqfeqlsgsilwmapevirmqdsnpysfqsdvyafgivlyelmtgqlpysninnrdqiiemvgrgslspdlskvrsncpkrmkrlmaeclkkkrderpsfprilaeieelarelsg
PDB Details
| PDB code | 4R5Y |
| HET ID | B801 |
| HET name | 3K3 |
| Receptor Chain | B |
Other Details
| Target Type | Enzyme |
| Affinity | 7.5 |
| Affinity type | pIC50 |
? Sequence length |
132 |
? Proportion of original chain length |
44.9% |
? Internal contacts |
3434 |
? External contacts |
327 |
? Contact ratio |
10.501529 |
Features
Residue Distances