Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
with AMG319
Structure
Sequence
seesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekcKVMaskkkPlWlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesldlcllpYgcistgdkigmIEIVkdATtiakiqqstvgntgafkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndniMitetgnlfhIdfghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsa
PDB Details
| PDB code | 4WWN |
| HET ID | A1203 |
| HET name | 3VC |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 6.1 |
| Affinity type | pIC50 |
? Sequence length |
162 |
? Proportion of original chain length |
16.8% |
? Internal contacts |
4256 |
? External contacts |
587 |
? Contact ratio |
7.250426 |
Features
Residue Distances