Human B-Raf proto-oncogene, serine/threonine kinase
with sorafenib
GtoP Target: B-Raf proto-oncogene, serine/threonine kinase
Structure
Sequence
ddweipdgqitvgqrIgsgsfgtVykgkwhgdvAvkmlnvtaptpqqlqafknEvgvLrktrhvniLlfmgystapqlaivTQWCegsslyhhlhiietkfemiklidiarqtaqgmdyLhaksiiHrdlksnniFlhedltvkIGDFglatvksrwsgshqfeqlsgsilwmapevirmqdknpysfqsdvyafgivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpkamkrlmaeclkkkrderplfpqilasiellarslpk
PDB Details
| PDB code | 1UWH |
| HET ID | A1723 |
| HET name | BAX |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 7.7 |
| Affinity type | pIC50 |
? Sequence length |
133 |
? Proportion of original chain length |
47.8% |
? Internal contacts |
3610 |
? External contacts |
395 |
? Contact ratio |
9.13924 |
Features
Residue Distances