Human KIT proto-oncogene receptor tyrosine kinase
with sunitinib
GtoP Target: KIT proto-oncogene receptor tyrosine kinase
Structure
Sequence
gptykylqkpmyevqwkvveeingnnyvyidptqlpydhkwefprnrlsfgktLgagafgkVveataygliksdaamtvAvkmlkpsahlterealmselkvlsylgnhmnivnllgactiggptlviTEYCCyGdllnflrrkrdsficsktspaimeddelaldledllsfsyqvakgmaflaskncihrdlaarniLlthgritkiCDFglardikndsnyvvkgnarlpvkwmapesifncvytfesdvwsygiflwelfslgsspypgmpvdskfykmikegfrmlspehapaemydimktcwdadplkrptfkqivqliekqisestnhi
PDB Details
| PDB code | 3G0E |
| HET ID | A9000 |
| HET name | B49 |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 7.9 |
| Affinity type | pIC50 |
? Sequence length |
159 |
? Proportion of original chain length |
47.0% |
? Internal contacts |
4050 |
? External contacts |
547 |
? Contact ratio |
7.4040217 |
Features
Residue Distances