Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
with AZD6482
Structure
Sequence
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekcKvMaskkkplWlefkcadptalsnetigiIfKhgddlrqdmlilqilrimesiwetesldlcllpygcistgdkigmIEIVkdattiaKiqqstvgntgafkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndnimitetgnlfhIDfghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsahhhhhh
PDB Details
| PDB code | 4URK |
| HET ID | A2092 |
| HET name | A82 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 6.0 |
| Affinity type | pIC50 |
? Sequence length |
163 |
? Proportion of original chain length |
16.8% |
? Internal contacts |
4171 |
? External contacts |
612 |
? Contact ratio |
6.8153596 |
Features
Residue Distances