Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
with pictilisib
Structure
Sequence
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekcKvMAskkkplwlefkcadptalsnetigiIfKhgDdlrqDmlilqilrimesiwetesldlcllpYgcistgdkigmIEIvkdatTiakiqqstvgntgafkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndniMitetgnlfhIDfghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsa
PDB Details
| PDB code | 3DBS |
| HET ID | A1 |
| HET name | GD9 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 7.1 |
| Affinity type | pIC50 |
? Sequence length |
163 |
? Proportion of original chain length |
16.9% |
? Internal contacts |
4093 |
? External contacts |
550 |
? Contact ratio |
7.441818 |
Features
Residue Distances