Human mitogen-activated protein kinase 14
with VX-745
GtoP Target: mitogen-activated protein kinase 14
Structure
Sequence
gshsqerptfyrqelnktiwevperyqnlspVgsgaygsVcaafdtktglrvAvKklsrpfqsiihakrtyrelrlLkhmkhenvigLldvftparsleefndvyLVThLMGADlnnivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkiLdfglarhtddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppldqeemes
PDB Details
| PDB code | 3ZSI |
| HET ID | A1000 |
| HET name | 52P |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 8.0 |
| Affinity type | pIC50 |
? Sequence length |
138 |
? Proportion of original chain length |
37.8% |
? Internal contacts |
3591 |
? External contacts |
609 |
? Contact ratio |
5.8965516 |
Features
Residue Distances