Human farnesyltransferase, CAAX box, beta
with tipifarnib
GtoP Target: farnesyltransferase, CAAX box, beta
Structure
Sequence
maspssftyycppssspvwseplyslrpeharerlqddsvetvtsieqakveekiqevfssykfnhlvprlvlqrekhfhylkrglrqltdayecLdasrpwlcyWilhslelldepipqivatdvcqflelcqspeggfgggpgqyphlaptyaavnalciigteeaydiinrekllqylyslkqpdgsflmhvggevdvrsaycaasvasltniitpdlfegtaewiarcqnweggiggvpgmeahggytfcglaalvilkrerslnlksllqwvtsrqmrfeggfqgrcnklvDgCYsfwqagllpllhralhaqgdpalsmshwmfhqqalqeyilmccqcpagglldkpgksrDfYHtcyclsglsiaqhfgsgamlhdvvlgvpenalqpthpvynigpdkviqattyflqkpvpgfeelkdetsaepatd
PDB Details
| PDB code | 1SA4 |
| HET ID | B441 |
| HET name | JAN |
| Receptor Chain | B |
Other Details
| Target Type | Enzyme |
| Affinity | 9.1 |
| Affinity type | pIC50 |
? Sequence length |
267 |
? Proportion of original chain length |
60.9% |
? Internal contacts |
7433 |
? External contacts |
718 |
? Contact ratio |
10.352367 |
Features
Residue Distances