Human HCK proto-oncogene, Src family tyrosine kinase
with PP121
GtoP Target: HCK proto-oncogene, Src family tyrosine kinase
Structure
Sequence
gamgsgiriivvalydyeaihhedlsfqkgdqmvvleesgewwkarslatrkegyipsnyvarvdsleteewffkgisrkdaerqllapgnmlgsfmirdsettkgsyslsvrdydprqgdtvkhykirtldnggfyisprstfstlqelvdhykkgndglcqklsvpcmsskpqkpwekdaweipreslklekkLgagqfgeVwmatynkhtkvAvktmkpgsmsveaflaeanvmktlqhdklvklhavvtkepiyiiTEFMakgSlldflksdegskqplpklidfsaqiaegmafieqrnyihrdlraaniLvsaslvckiADfglarviedneytaregakfpikwtapeainfgsftiksdvwsfgillmeivtygripypgmsnpeviralergyrmprpencpeelynimmrcwknrpeerptfeyiqsvlddfytatesqeeip
PDB Details
| PDB code | 3VS7 |
| HET ID | B601 |
| HET name | KS1 |
| Receptor Chain | B |
Other Details
| Target Type | Enzyme |
| Affinity | 8.1 |
| Affinity type | pIC50 |
? Sequence length |
132 |
? Proportion of original chain length |
28.9% |
? Internal contacts |
3276 |
? External contacts |
386 |
? Contact ratio |
8.487046 |
Features
Residue Distances