Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
with PF-04691502
Structure
Sequence
gsvgnreekilnreigfaigmpvcefdmvkdpevqdfrrnilnvckeavdlrdlnsphsramyvyppnvesspelpkhiynkldkgqiivviwvivspnndkqkytlkinhdcvpeqviaeairkktrsmllsseqlklcvleyqgkyilkvcgcdeyflekyplsqykyirscimlgrmpnlmlmakeslysqlpmdcftmpsysrristatpymngetstkslwvinsalrikilcatyvnvnirdidkiyvrtgiyhggeplcdnvntqrvpcsnprwnewlnydiyipdlpraarlclsicsvkgrkgakeehcplawgninlfdytdtlvsgkmalnlwpvphgledllnpigvtgsnpnketpclelefdwfssvvkfpdmsvieehanwsvsreagfsyshaglsnrlardnelrendkeqlkaistrdplseiteqekdflwshrhycvtipeilpklllsvkwnsrdevaqmyclvkdwppikpeqamelldcnypdpmvrgfavrclekyltddklsqyliqlvqvlkyeqyldnllvrfllkkaltnqrighfffwhlksemhnktvsqrfglllesycracgmylkhlnrqveameklinltdilkqekkdetqkvqmkflveqmrrpdfmdalqgflsplnpahqlgnlrleecRiMssakrplwlnwenpdimsellfqnneiIfKngddlrqDmltlqiirimeniwqnqgldlrmlpYgclsigdcvgliEvVrnshtimQiqckgglkgalqfnshtlhqwlkdknkgeiydaaidlftrscagycvatfilgigdrhnsniMvkddgqlfhIDfghfldhkkkkfgykrervpfvltqdfliviskgaqectktreferfqemcykaylairqhanlfinlfsmmlgsgmpelqsfddiayirktlaldkteqealeyfmkqmndahh
PDB Details
| PDB code | 4TV3 |
| HET ID | A1101 |
| HET name | ML9 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 9.2 |
| Affinity type | pKi |
? Sequence length |
164 |
? Proportion of original chain length |
17.2% |
? Internal contacts |
3877 |
? External contacts |
517 |
? Contact ratio |
7.499033 |
Features
Residue Distances