Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
with apitolisib
Structure
Sequence
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekcKvMaSkkkplwlefkcadptalsnetigiIfKhgDdLrqDmlilqilrimesiwetesldlcllpygcistgdkigmIEIVkdattiakiqqstvgntgafkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndniMitetgnlFhiDfghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsahhhhhh
PDB Details
| PDB code | 3TL5 |
| HET ID | A1 |
| HET name | 980 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 7.8 |
| Affinity type | pIC50 |
? Sequence length |
163 |
? Proportion of original chain length |
16.8% |
? Internal contacts |
4319 |
? External contacts |
542 |
? Contact ratio |
7.9686346 |
Features
Residue Distances