Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
with wortmannin
Structure
Sequence
msyyhhhhhhdypssgelwgihlmpprpssgelwgihlmpprilvecllpngmivtleclreatlitikhelfkearkyplhqllqdessyifvsvtqeaereeffdetrrlcdlrlfqpflkviepvgnreekilnreigfaigmpvcefdmvkdpevqdfrrnilnvckeavdlrdlnsphsramyvyppnvesspelpkhiynkldkgqiivviwvivspnndkqkytlkinhdcvpeqviaeairkktrsmLlsseqlklcvleyqgkyilkvcgcdeyflekyplsqykyirscimlgrmpnlmlmakeslysqlpmdcftmpsysrristatpymngetstkslwvinsalrikilcatyvnvnirdidkiyvrtgiyhggeplcdnvntqrvpcsnprwnewlnydiyipdlpraarlclsicsvkgrkgakeehcplawgninlfdytdtlvsgkmalnlwpvphgledllnpigvtgsnpnketpclelefdwfssvvkfpdmsvieehanwsvsreagfsyshaglsnrlardnelrendkeqlkaistrdplseiteqekdflwshrhycvtipeilpklllsvkwnsrdevaqmyclvkdwppikpeqamelldcnypdpmvrgfavrclekyltddklsqyliqlvqvlkyeqyldnllvrfllkkaltnqrighfffwhlksemhnktvsqrfglllesycracgmylkhlnrqveameklinltdilkqekkdetqkvqmkflveqmrrpdfmdalqgflsplnpahqlgnlrleecrimsSaKrPlWlnwenpdimsellfqnneiIfKngddlrqdmltlqiirimeniwqnqgldlrmlpYgclsigdcvgliEVVrnshtimqiqckgglkgalqfnshtlhqwlkdknkgeiydaaidlftrscagycvatfilgigdrhnsnimvkddgqlfhIDfghfldhkkkkfgykrervpfvltqdfliviskgaqectktreferfqemcykaylairqhanlfinlfsmmlgsgmpelqsfddiayirktlaldkteqealeyfmkqmndarhggwttkmdwifhtikqhaln
PDB Details
| PDB code | 3HHM |
| HET ID | A1833 |
| HET name | KWT |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 6.9 |
| Affinity type | pKi |
? Sequence length |
701 |
? Proportion of original chain length |
64.2% |
? Internal contacts |
18605 |
? External contacts |
1124 |
? Contact ratio |
16.55249 |
Features
Residue Distances