Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
with PI 3-Kg inhibitor II
Structure
Sequence
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvrllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekckvmaskkkPlWlefkcadptalsnetigiifKhgddlrqdmlilqilrimesiwetesldlcllpYgcistgdkigmIEIVkdAttiakiqqstvgntgafkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndniMitetgnlfhIDfghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsahhhhhh
PDB Details
| PDB code | 2A4Z |
| HET ID | A101 |
| HET name | BYM |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 6.6 |
| Affinity type | pIC50 |
? Sequence length |
155 |
? Proportion of original chain length |
15.9% |
? Internal contacts |
3993 |
? External contacts |
535 |
? Contact ratio |
7.4635515 |
Features
Residue Distances