Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
with PI 3-Kg inhibitor
Structure
Sequence
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvrllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekckvmaskkkPlwlefkcadptalsnetigiIfKhgDdlrqdmlilqilrimesiwetesldlcllpygcistgdkigmIEiVkdattiakiqqstvgntgafkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhndniMitetgnlFhIDfghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsahhhhhh
PDB Details
| PDB code | 2A5U |
| HET ID | A101 |
| HET name | QYT |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 8.1 |
| Affinity type | pIC50 |
? Sequence length |
155 |
? Proportion of original chain length |
15.9% |
? Internal contacts |
4154 |
? External contacts |
622 |
? Contact ratio |
6.678457 |
Features
Residue Distances