Human anaplastic lymphoma receptor tyrosine kinase
with brigatinib
GtoP Target: anaplastic lymphoma receptor tyrosine kinase
Structure
Sequence
gstsnpnycfagktssisdlkevprknitlirgLghgafgevyegqvsgmpndpsplqvAvktlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfilLElMAgGdlksflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarncLltcpgpgrvakigDfgmardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygplvee
PDB Details
| PDB code | 5J7H |
| HET ID | A1501 |
| HET name | 6GY |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 9.4 |
| Affinity type | pIC50 |
? Sequence length |
149 |
? Proportion of original chain length |
46.4% |
? Internal contacts |
3768 |
? External contacts |
459 |
? Contact ratio |
8.20915 |
Features
Residue Distances