Human SRC proto-oncogene, non-receptor tyrosine kinase
with saracatinib
GtoP Target: SRC proto-oncogene, non-receptor tyrosine kinase
Structure
Sequence
gsnkskpkdasqrrrslepaenvhgagggafpasqtpskpasadghrgpsaafapaaaepklfggfnssdtvtspqragplaggvttfvalydyesrtetdlsfkkgerlqivnntegdwwlahslstgqtgyipsnyvapsdsiqaeewyfgkitrreserlllnaenprgtflvresettkgayclsvsdfdnakglnvkhykirkldsggfyitsrtqfnslqqlvayyskhadglchrlttvcptskpqtqglakdaweipreslrlevkLgqgcfgeVwmgtwngttrvAiKtlkpgtmspeaflqeaqvmkklrheklvqlyavvseepiyivTEYMSkGslldflkgetgkylrlpqlvdmaaqiasgmayvermnyvhrdlraaniLvgenlvckvaDfglarliedneytarqgakfpikwtapeaalygrftiksdvwsfgilltelttkgrvpypgmvnrevldqvergyrmpcppecpeslhdlmcqcwrkepeerptfeylqafledyftstepqqpgenl
PDB Details
| PDB code | 2H8H |
| HET ID | A534 |
| HET name | H8H |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 8.6 |
| Affinity type | pIC50 |
? Sequence length |
132 |
? Proportion of original chain length |
24.5% |
? Internal contacts |
3441 |
? External contacts |
500 |
? Contact ratio |
6.882 |
Features
Residue Distances