Human aldo-keto reductase family 1 member B
with tolrestat
GtoP Target: aldo-keto reductase family 1 member B
Structure
Sequence
masrillnngakmpilglgtWksppgqvteavkvaidvgyrhidcahVYqnenevgvaiqeklreqvvkreelfivsklWctyhekglvkgacqktlsdlkldyldlyliHWpTgFkpgkefFpldesgnVvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykpavnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaakhnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvCaLlSCtshkdypfheef
PDB Details
| PDB code | 2FZD |
| HET ID | A317 |
| HET name | TOL |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 7.3 |
| Affinity type | pIC50 |
? Sequence length |
284 |
? Proportion of original chain length |
89.6% |
? Internal contacts |
8668 |
? External contacts |
295 |
? Contact ratio |
29.38305 |
Features
Residue Distances