Human anaplastic lymphoma receptor tyrosine kinase
with ceritinib
GtoP Target: anaplastic lymphoma receptor tyrosine kinase
Structure
Sequence
msyyhhhhhhdydipttenlyfqgamgselqspeyklsklrtstimtdynpnycfagktssisdlkevprknitlirgLgHGafgevyegqvsgmpndpsplqvAvKtlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfilLElMAgGDlkSflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarncLltcpgpgrvakigdfgmardiyragyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygplveeeek
PDB Details
| PDB code | 4MKC |
| HET ID | A1503 |
| HET name | 4MK |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 9.7 |
| Affinity type | pIC50 |
? Sequence length |
135 |
? Proportion of original chain length |
36.5% |
? Internal contacts |
3311 |
? External contacts |
672 |
? Contact ratio |
4.9270835 |
Features
Residue Distances