Human DOT1 like histone lysine methyltransferase
with SGC0946
GtoP Target: DOT1 like histone lysine methyltransferase
Structure
Sequence
gmgeklelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipdlklamenYvlidydtksfesmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhilqqvynhsvtdpeklnnyepfspevygetsfdlvaqmideikmtdddlfvDlGSGvgqVvlqvaaatnckhhygvEKAdipakyaetmdrefrkwmkwygkkhaeytlerGDFlseewreriantsviFvNnfaFgpevdhqlkerfanmkeggriVSskpfaplnfrinsrnlsdigtimrvvelsplkgsvswtgkpvsYylhtidrtilenyfsslknpklreeqeaarrrqqresksnaatptkgpegkvagpadapmdsgaeeekagaatvkkpspskarkkklnkkgrkmagrkrg
PDB Details
| PDB code | 4ER6 |
| HET ID | A502 |
| HET name | AW2 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 9.5 |
| Affinity type | pIC50 |
? Sequence length |
255 |
? Proportion of original chain length |
61.5% |
? Internal contacts |
6768 |
? External contacts |
525 |
? Contact ratio |
12.891429 |
Features
Residue Distances