Human DOT1 like histone lysine methyltransferase
with EPZ004777
GtoP Target: DOT1 like histone lysine methyltransferase
Structure
Sequence
gmgeklelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipdlklamenyvlidydtksfesmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhilqqvynhsvtdpeklnnyepfspevygetsfdlvaqMideikmtdddlfvDlGSgvgqVvlqvaaatnckhhygvEKadipakyaetmdrefrkwmkwygkkhaeytlerGDFlseewreriantsvifvNnfaFgpevdhqlkerfanmkeggrivSskpfaplnfrinsrnlsdigtimrvvelsplkgsvswtgkpvsYylhtidrtilenyfsslknpklreeqeaarrrqqresks
PDB Details
| PDB code | 4ER3 |
| HET ID | A401 |
| HET name | 0QK |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 9.4 |
| Affinity type | pIC50 |
? Sequence length |
166 |
? Proportion of original chain length |
46.9% |
? Internal contacts |
4291 |
? External contacts |
469 |
? Contact ratio |
9.149254 |
Features
Residue Distances