Human DOT1 like histone lysine methyltransferase
with pinometostat
GtoP Target: DOT1 like histone lysine methyltransferase
Structure
Sequence
hhhhhhssgmgeklelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipdlklamenyvlidydtksfesmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhilqqvynhsvtdpeklnnyepfspevygetsfdlvaqmideikmtdddlfvDlGSGvgqVvlqvaaatnckhhygVEKadipakyaetmdrefrkwmkwygkkhaeytlerGDFlseewreriantsviFvNnfafgpevdhqlkerfanmkeggrivsskpfaplnfrinsrnlsdigtimrvvelsplkgsvswtgkpvsyylhtidrtilenyfsslknpklreeqeaarrrqqresksnaatptkgpegkvagpadapmdsgaeeekagaatvkkpspskarkkklnkkgrkmagrkrgrpkk
PDB Details
| PDB code | 4HRA |
| HET ID | A501 |
| HET name | EP6 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 10.1 |
| Affinity type | pKi |
? Sequence length |
81 |
? Proportion of original chain length |
18.8% |
? Internal contacts |
2122 |
? External contacts |
382 |
? Contact ratio |
5.5549736 |
Features
Residue Distances