Human DOT1 like histone lysine methyltransferase
with bromo-deaza-SAH
GtoP Target: DOT1 like histone lysine methyltransferase
Structure
Sequence
gmgeklelrlkspvgaepavypwplpvydkhhdaaheiietirwvceeipdlklamenyvlidydtksfesmqrlcdkynraidsihqlwkgttqpmklntrpstgllrhilqqvynhsvtdpeklnnyepfsPevyGETsfdlvaqmideikmtdddlfvDlGSgvgQvvlqvaaatnckhhygvEKadipakyaetmdrefrkwmkwygkkhaeytlerGDFlseewreriantsviFvNnfaFgpevdhqlkerfanmkeggrivsskpfaplnfrinsrnlsdigtimrvvelsplkgsvswtgkpvsyylhtidrtilenyfsslknpklreeqeaarrrqqresksnaatptkgpegkvagpadapmdsgaeeekagaatvkkpspskarkkklnkkgrkmagrkrgrpkkmnta
PDB Details
| PDB code | 3SX0 |
| HET ID | A421 |
| HET name | SX0 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 7.1 |
| Affinity type | pIC50 |
? Sequence length |
113 |
? Proportion of original chain length |
26.6% |
? Internal contacts |
3094 |
? External contacts |
451 |
? Contact ratio |
6.8603106 |
Features
Residue Distances