Human MET proto-oncogene, receptor tyrosine kinase
with crizotinib
GtoP Target: MET proto-oncogene, receptor tyrosine kinase
Structure
Sequence
mvhidlsalnpelvqavqhvvigpsslivhfnevIGrghfgcvyhgtlldndgkkihcAvkslnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvLPYMkhGdlrnfirnethnptvkdligfglqvakgmkylaskkfvhrdlaaRncMldekftvkvADfglardmYdkeyysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfigehhhhhhhh
PDB Details
| PDB code | 2WGJ |
| HET ID | A2346 |
| HET name | VGH |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 9.1 |
| Affinity type | pIC50 |
? Sequence length |
147 |
? Proportion of original chain length |
47.7% |
? Internal contacts |
3771 |
? External contacts |
406 |
? Contact ratio |
9.2881775 |
Features
Residue Distances