Human acetylcholinesterase (Cartwright blood group)
with donepezil
GtoP Target: acetylcholinesterase (Cartwright blood group)
Structure
Sequence
gredaellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdattfqsvcyqYvdtlypgfegtemWnpnrelsedclylnvwtpyprptsptpvlvwiygggfYsgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvqenvaafggdptsvtlfgEsagaasvgmhllsppsrglfhravlqsgapngpwatvgmgearrratqlahlvgcppggtggndtelvaclrtrpaqvlvnheWhvlpqeSvFrfsfvpvvdgdflsdtpealinagdfhglqvlvgvvkdegsYFlvYgapgfskdneslisraeflagvrvgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyayvfehrastlswplwmgvpHgyeiefifgipldpsrnytaeekifaqrlmrywanfartgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpkllsat
PDB Details
| PDB code | 4EY7 |
| HET ID | A604 |
| HET name | E20 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 8.3 |
| Affinity type | pIC50 |
? Sequence length |
376 |
? Proportion of original chain length |
69.2% |
? Internal contacts |
10348 |
? External contacts |
883 |
? Contact ratio |
11.719139 |
Features
Residue Distances