synpharm
A database of ligand-responsive protein sequences...

lenvatinib

PEP - lenvatinib
RCSB PDB Ligand - LEV
CAS Registry No. - 417716-92-8
ChEMBL Ligand - CHEMBL1289601
PubChem CID - 9823820
Wikipedia - Lenvatinib
DrugCentral Ligand - 4942
Reactome Drug - R-ALL-2023393
Reactome Reaction - R-HSA-9669854
Reactome Reaction - R-HSA-9669900
Reactome Reaction - R-HSA-9674430
Reactome Reaction - R-HSA-9674095
Reactome Reaction - R-HSA-2077424
Reactome Reaction - R-HSA-2077420
Structure
Molecular Details
Molecular mass (Da) 426.1095
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Polar surface area (A2) 115.57
Lipinski rules broken 0
logP 2.295
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source FDA & EMA (2015)
Responsive Sequences
kinase insert domain receptor (157 residues)