synpharm
A database of ligand-responsive protein sequences...

tacrolimus

CAS Registry No. - 104987-11-3
ChEMBL Ligand - CHEMBL269732
DrugBank Ligand - DB00864
PubChem CID - 445643
Wikipedia - Tacrolimus
RCSB PDB Ligand - FK5
Immunopaedia Search - tacrolimus
Reactome Drug - R-ALL-9678991
Reactome Reaction - R-HSA-9690461
Structure
Molecular Details
Molecular mass (Da) 803.482
Hydrogen bond acceptors 13
Hydrogen bond donors 3
Polar surface area (A2) 178.36
Lipinski rules broken 1
logP 3.309
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source FDA (1994), EMA (2002)
Responsive Sequences
FK506 binding protein 1A (74 residues)