synpharm
A database of ligand-responsive protein sequences...

imatinib

CAS Registry No. - 152459-95-5
ChEBI - CHEBI:45783
ChEMBL Ligand - CHEMBL941
DrugBank Ligand - DB00619
PubChem CID - 5291
Wikipedia - Imatinib
PEP - imatinib
RCSB PDB Ligand - STI
DrugCentral Ligand - 1423
Reactome Drug - R-ALL-9659761
Reactome Reaction - R-HSA-9669854
Reactome Reaction - R-HSA-9674430
Reactome Reaction - R-HSA-9674095
Reactome Reaction - R-HSA-9669900
Reactome Reaction - R-HSA-9669859
Reactome Reaction - R-HSA-9674397
Structure
Molecular Details
Molecular mass (Da) 493.259
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Polar surface area (A2) 86.28
Lipinski rules broken 0
logP 4.265
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source FDA (2001)
Responsive Sequences
ABL proto-oncogene 1, non-receptor tyrosine kinase (135 residues)