synpharm
A database of ligand-responsive protein sequences...

axitinib

CAS Registry No. - 319460-85-0
ChEMBL Ligand - CHEMBL1289926
DrugBank Ligand - DB06626
PubChem CID - 6450551
RCSB PDB Ligand - AXI&sid=4AG8
Wikipedia - Axitinib
PEP - axitinib
RCSB PDB Ligand - AXI
DrugCentral Ligand - 4225
Reactome Drug - R-ALL-9669719
Reactome Reaction - R-HSA-9674095
Reactome Reaction - R-HSA-9674430
Reactome Reaction - R-HSA-9669854
Reactome Reaction - R-HSA-9669900
Structure
Molecular Details
Molecular mass (Da) 386.12012
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Polar surface area (A2) 95.97
Lipinski rules broken 1
logP 5.771
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source FDA and EMA (2012)
Responsive Sequences
kinase insert domain receptor (150 residues)
kinase insert domain receptor (150 residues)