synpharm
A database of ligand-responsive protein sequences...

sapropterin

CAS Registry No. - 17528-72-2
ChEBI - CHEBI:59560
ChEMBL Ligand - CHEMBL1201774
DrugBank Ligand - DB00360
Human Metabolome Database - HMDB00787
PubChem CID - 44257
Wikipedia - Tetrahydrobiopterin
RCSB PDB Ligand - H4B
DrugCentral Ligand - 2612
PubChem CID - 135398654
Structure
Molecular Details
Molecular mass (Da) 241.1175
Hydrogen bond acceptors 8
Hydrogen bond donors 6
Polar surface area (A2) 119.64
Lipinski rules broken 1
logP -1.176
Other Details
Ligand type Metabolite
Radiolabelled No
Approved Yes
Approval Source FDA (2007), EMA (2008)
Responsive Sequences
L-Phenylalanine hydroxylase (86 residues)