synpharm
A database of ligand-responsive protein sequences...

gefitinib

CAS Registry No. - 184475-35-2
ChEBI - CHEBI:49668
ChEMBL Ligand - CHEMBL939
DrugBank Ligand - DB00317
PubChem CID - 123631
Wikipedia - Gefitinib
PEP - gefitinib
RCSB PDB Ligand - IRE
DrugCentral Ligand - 1282
Reactome Drug - R-ALL-1169429
Reactome Reaction - R-HSA-9665121
Reactome Reaction - R-HSA-1220610
Structure
Molecular Details
Molecular mass (Da) 446.1521
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Polar surface area (A2) 68.74
Lipinski rules broken 0
logP 3.056
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source FDA (2003), EMA (2009)
Responsive Sequences
epidermal growth factor receptor (138 residues)
epidermal growth factor receptor (138 residues)