synpharm
A database of ligand-responsive protein sequences...

17β-estradiol

CAS Registry No. - 50-28-2
ChEBI - CHEBI:16469
ChEMBL Ligand - CHEMBL135
DrugBank Ligand - DB00783
Human Metabolome Database - HMDB00151
Lipid Maps - LMST02010001
NURSA Ligand - 10.1621/BVEO4KVZVC
PharmGKB Drug - PA449503
PubChem CID - 5757
RCSB PDB Ligand - EST
Wikipedia - Estradiol
PEP - estradiol
DrugCentral Ligand - 1057
GPCRdb Ligand - 1013
Structure
Molecular Details
Molecular mass (Da) 272.17764
Hydrogen bond acceptors 1
Hydrogen bond donors 2
Polar surface area (A2) 40.46
Lipinski rules broken 0
logP 4.646
Other Details
Ligand type Metabolite
Radiolabelled No
Approved Yes
Approval Source FDA (1954, prior history unavailable)
Responsive Sequences
Estrogen receptor-α (173 residues)
Estrogen receptor-β (182 residues)