Data and Statistics
Ligands by Type
A breakdown of the ligands in the SynPharm database by Guide to PHARMACOLOGY
type.
| Synthetic Organic | 459 |
| Metabolite | 34 |
| Natural Product | 13 |
| Peptide | 6 |
| Inorganic | 1 |
| Antibody | 2 |
Ligands by Mass
A breakdown of the ligands in the SynPharm database by mass.
| Ligand Mass (Da) | Count |
|---|---|
| 0 - 50 | 1 |
| 100 - 150 | 2 |
| 150 - 200 | 10 |
| 200 - 250 | 27 |
| 250 - 300 | 46 |
| 300 - 350 | 73 |
| 350 - 400 | 85 |
| 400 - 450 | 88 |
| 450 - 500 | 75 |
| 500 - 550 | 41 |
| 550 - 600 | 30 |
| 600 - 650 | 12 |
| 650 - 700 | 8 |
| 700 - 750 | 3 |
| 750 - 800 | 3 |
| 800 - 850 | 2 |
| 900 - 950 | 1 |
| 950 - 1000 | 1 |
| 1200 - 1250 | 1 |
| 1750 - 1800 | 1 |
| 3050 - 3100 | 1 |
| 9350 - 9400 | 1 |
| 16050 - 16100 | 1 |
| 43200 - 43250 | 1 |
| 46750 - 46800 | 1 |
Ligands by Approval Status
A breakdown of the ligands in the SynPharm database by approval status.
| Approved | 111 |
| Not Approved | 404 |
Sequences by Target Type
A breakdown of the sequences in the SynPharm database by Guide to PHARMACOLOGY
target type.
| GPCR | 67 |
| LGIC | 4 |
| VGIC | 3 |
| Other Ion Channel | 0 |
| NHR | 106 |
| Enzyme | 392 |
| Catalytic Receptor | 42 |
| Transporter | 4 |
| Other Protein | 26 |
Sequences by Length
A breakdown of the sequences in the SynPharm database by sequence length.
| Sequence Length (residues) | Count |
|---|---|
| 0 - 50 | 3 |
| 50 - 100 | 76 |
| 100 - 150 | 222 |
| 150 - 200 | 160 |
| 200 - 250 | 53 |
| 250 - 300 | 49 |
| 300 - 350 | 32 |
| 350 - 400 | 19 |
| 400 - 450 | 14 |
| 450 - 500 | 3 |
| 500 - 550 | 2 |
| 550 - 600 | 4 |
| 600 - 650 | 6 |
| 650 - 700 | 0 |
| 700 - 750 | 1 |
Sequence Contiguity by Target Type
This is a measure of how close together on the sequence the actual
binding residues are - sequences with low contiguity will have widely
separated residues. Here it is represented as the proportion of binding
residues to non-binding residues.