Human mitogen-activated protein kinase 10
with tanzisertib
GtoP Target: mitogen-activated protein kinase 10
Structure
Sequence
mslhflyycseptldvkiafcqgfdkqvdvsyiakhynmskskvdnqfysvevgdstftvlkryqnlkpIgsgaqgiVcaaydavldrnvAiKklsrpfqnqthakrayrelvlMkcvnhkniIsLlnvftpqktleefqdvyLvMelMdANlcQviqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkiLdfglartagtsfmmtpyvvtryyrapevilgmgykenvdiwsvgcimgemvrhkilfpgrdyidqwnkvieqlgtpcpefmkklqptvrnyvenrpkyagltfpklfpdslfpadsehnklkasqardllskmlvidpakrisvddalqhpyinvwydpaeveapppqiydkqlderehtieewkeliykevmnseektkngvvkgqpspsgaavnsseslppsssvndissmstdqtlasdtdssleasagplgccr
PDB Details
| PDB code | 3TTI |
| HET ID | A465 |
| HET name | KBI |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 8.2 |
| Affinity type | pIC50 |
? Sequence length |
137 |
? Proportion of original chain length |
29.3% |
? Internal contacts |
3626 |
? External contacts |
588 |
? Contact ratio |
6.1666665 |
Features
Residue Distances