Human phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
with omipalisib
Structure
Sequence
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkeewplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqviemlqkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekckvMaSkkkPlWlefkcadptalsnetigiIfKhgddlrqdmlilqilrimesiwetesldlcllpYgcistgdkigmIEIVkdattiakiqqstvgntgafkdevlnhwlkekspteekfqaaverfvyscagycvatfvlgigdrhnDNiMitetgnlfhiDfghilgnyksflginkervpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpqltskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsahhhhhh
PDB Details
| PDB code | 3L08 |
| HET ID | A1109 |
| HET name | ZIG |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 7.6 |
| Affinity type | pKi |
? Sequence length |
161 |
? Proportion of original chain length |
16.6% |
? Internal contacts |
4033 |
? External contacts |
531 |
? Contact ratio |
7.5951037 |
Features
Residue Distances