Human MET proto-oncogene, receptor tyrosine kinase
with tepotinib
GtoP Target: MET proto-oncogene, receptor tyrosine kinase
Structure
Sequence
lsalnpelvqavqhvvigpsslivhfnevIgrghfgcvyhgtlldndgkkihcAvkslnritdigevsqfltegiimkdfshpnvLsllgiclrsegsplvvLPYMKhGDlrnfirnethnptvkdligfglqvakgmkylaskkfvhrdlaaRncMldekftvkvADfglArdmYdkeyysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfi
PDB Details
| PDB code | 4R1V |
| HET ID | A1401 |
| HET name | 3E8 |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 8.5 |
| Affinity type | pIC50 |
? Sequence length |
147 |
? Proportion of original chain length |
50.2% |
? Internal contacts |
4141 |
? External contacts |
389 |
? Contact ratio |
10.645245 |
Features
Residue Distances