Human spleen associated tyrosine kinase
with entospletinib
GtoP Target: spleen associated tyrosine kinase
Structure
Sequence
maleeirpkevyldrklltledkeLgSgnFgtvkkgyyqmkkvvktvAvkilkneandpalkdellaeanvmqqldnpyivrmigiceaeswmlvmEmAElGplnkylqqnrhvkdkniielvhqvsmgmkyleesnfvhrdlaarnvLlvtqhyakisDfglskalradenyykaqthgkwpvkwyapecinyykfssksdvwsfgvlmweafsygqkpyrgmkgsevtamlekgermgcpagcpremydlmnlcwtydvenrpgfaavelrlrnyyydvvneghhhhhh
PDB Details
| PDB code | 4PUZ |
| HET ID | B701 |
| HET name | CG9 |
| Receptor Chain | B |
Other Details
| Target Type | Enzyme |
| Affinity | 8.1 |
| Affinity type | pIC50 |
? Sequence length |
136 |
? Proportion of original chain length |
46.4% |
? Internal contacts |
3510 |
? External contacts |
451 |
? Contact ratio |
7.7827053 |
Features
Residue Distances