Human Pim-1 proto-oncogene, serine/threonine kinase
with ruboxistaurin
GtoP Target: Pim-1 proto-oncogene, serine/threonine kinase
Structure
Sequence
mllskinslahlraapcndlhatklapgkekeplesqyqvgplLGsggFgsVysgirvsdnlpvAiKhvekdrisdwgelpngtrvpmEvvllkkvssgfsgvIrlldwferpdsfvliLERPepVqDlfdfitergalqeelarsffwqvleavrhchncgvlhrdikdENiLidlnrgelklIDfgsgallkdtvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgdipfehdeeiiggqvffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqetaeihlhslspgps
PDB Details
| PDB code | 2J2I |
| HET ID | B1307 |
| HET name | LY4 |
| Receptor Chain | B |
Other Details
| Target Type | Enzyme |
| Affinity | 6.7 |
| Affinity type | pIC50 |
| Sequence length | 143 |
| Proportion of original chain length | 45.5% |
| Internal contacts | 3828 |
| External contacts | 398 |
| Contact ratio | 96.2% |
Features
Residue Distances