Human Pim-1 proto-oncogene, serine/threonine kinase
with ruboxistaurin
GtoP Target: Pim-1 proto-oncogene, serine/threonine kinase
Structure
Sequence
mllskinslahlraapcndlhatklapgkekeplesqyqvgplLGsggFgsVysgirvsdnlpvAiKhvekdrisdwgelpngtrvpmEvvllkkvssgfsgvIrlldwferpdsfvliLERPepVqDlfdfitergalqeelarsffwqvleavrhchncgvlhrdikdENiLidlnrgelklIDfgsgallkdtvytdfdgtrvysppewiryhryhgrsaavwslgillydmvcgdipfehdeeiiggqvffrqrvssecqhlirwclalrpsdrptfeeiqnhpwmqdvllpqetaeihlhslspgps
PDB Details
| PDB code | 2J2I |
| HET ID | B1307 |
| HET name | LY4 |
| Receptor Chain | B |
Other Details
| Target Type | Enzyme |
| Affinity | 6.7 |
| Affinity type | pIC50 |
? Sequence length |
143 |
? Proportion of original chain length |
45.5% |
? Internal contacts |
3828 |
? External contacts |
398 |
? Contact ratio |
9.618091 |
Features
Residue Distances