Human anaplastic lymphoma receptor tyrosine kinase
with brigatinib
GtoP Target: anaplastic lymphoma receptor tyrosine kinase
Structure
Sequence
gstsnpnycfagktssisdlkevprknitlirgLghgafgevyegqvsgmpndpsplqvAvktlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfilLElMAgGdlksflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarncLltcpgpgrvakigDfgmardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygplvee
PDB Details
| PDB code | 5J7H |
| HET ID | A1501 |
| HET name | 6GY |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 10.1 |
| Affinity type | pKi |
| Sequence length | 149 |
| Proportion of original chain length | 46.4% |
| Internal contacts | 3768 |
| External contacts | 459 |
| Contact ratio | 82.1% |
Features
Residue Distances