Human anaplastic lymphoma receptor tyrosine kinase
with ceritinib
GtoP Target: anaplastic lymphoma receptor tyrosine kinase
Structure
Sequence
msyyhhhhhhdydipttenlyfqgamgselqspeyklsklrtstimtdynpnycfagktssisdlkevprknitlirgLgHGafgevyegqvsgmpndpsplqvAvKtlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfilLElMAgGDlkSflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaarncLltcpgpgrvakigdfgmardiyragyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygplveeeek
PDB Details
| PDB code | 4MKC |
| HET ID | A1503 |
| HET name | 4MK |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 9.7 |
| Affinity type | pIC50 |
| Sequence length | 135 |
| Proportion of original chain length | 36.5% |
| Internal contacts | 3311 |
| External contacts | 672 |
| Contact ratio | 49.3% |
Features
Residue Distances