Human anaplastic lymphoma receptor tyrosine kinase
with crizotinib
GtoP Target: anaplastic lymphoma receptor tyrosine kinase
Structure
Sequence
mahhhhhhnpnycfagktssisdlkevprknitlirglghgafgevyegqvsgmpndpsplqvAvktlpevcseqdeldflmealiiskfnhqnivrcigvslqslprfilLElMAgGdlksflretrprpsqpsslamldllhvardiacgcqyleenhfihrdiaaRNcLltcpgpgrvakiGDfgmardiyrasyyrkggcamlpvkwmppeafmegiftsktdtwsfgvllweifslgympypsksnqevlefvtsggrmdppkncpgpvyrimtqcwqhqpedrpnfaiilerieyctqdpdvintalpieygplveeeekv
PDB Details
| PDB code | 2XP2 |
| HET ID | A9000 |
| HET name | VGH |
| Receptor Chain | A |
Other Details
| Target Type | CatalyticReceptor |
| Affinity | 9.0 |
| Affinity type | pIC50 |
? Sequence length |
123 |
? Proportion of original chain length |
37.3% |
? Internal contacts |
3155 |
? External contacts |
482 |
? Contact ratio |
6.5456433 |
Features
Residue Distances