Human dihydroorotate dehydrogenase (quinone)
with teriflunomide
GtoP Target: dihydroorotate dehydrogenase (quinone)
Structure
Sequence
matgderfyaehlMptlqglldPesaHrlAvrftslgllprarfqdsdmlevrvlghkfrnpvgiaagFdkhgeavdglykmgfgfveigsvtpkpqegnprprvfRlpedqavinrygfnshglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggvssgqdalekiragaslvqlYtaLTfwGPpvvgkvkreleallkeqgfggvtdaigadhrr
PDB Details
| PDB code | 1D3H |
| HET ID | A397 |
| HET name | A26 |
| Receptor Chain | A |
Other Details
| Target Type | Enzyme |
| Affinity | 7.5 |
| Affinity type | pKi |
? Sequence length |
322 |
? Proportion of original chain length |
87.5% |
? Internal contacts |
8862 |
? External contacts |
286 |
? Contact ratio |
30.986013 |
Features
Residue Distances