synpharm
A database of ligand-responsive protein sequences...

apixaban

CAS Registry No. - 503612-47-3
ChEBI - CHEBI:72296
ChEMBL Ligand - CHEMBL231779
DrugBank Ligand - DB06605
PubChem CID - 10182969
Wikipedia - Apixaban
PEP - apixaban
RCSB PDB Ligand - GG2
DrugCentral Ligand - 4298
Reactome Drug - R-ALL-9038732
Reactome Reaction - R-HSA-9015122
Reactome Reaction - R-HSA-9015111
Structure
Molecular Details
Molecular mass (Da) 459.19064
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Polar surface area (A2) 110.76
Lipinski rules broken 0
logP 2.432
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source EMA (2011), FDA (2012)
Responsive Sequences
coagulation factor X (134 residues)