synpharm
A database of ligand-responsive protein sequences...

sirolimus

CAS Registry No. - 53123-88-9
ChEBI - CHEBI:9168
ChEMBL Ligand - CHEMBL413
DrugBank Ligand - DB00877
PubChem CID - 5284616
Wikipedia - Sirolimus
PEP - sirolimus
RCSB PDB Ligand - RAP
DrugCentral Ligand - 2446
Reactome Drug - R-ALL-9678687
Reactome Reaction - R-HSA-9679044
Structure
Molecular Details
Molecular mass (Da) 913.5551
Hydrogen bond acceptors 14
Hydrogen bond donors 3
Polar surface area (A2) 195.43
Lipinski rules broken 1
logP 4.321
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source FDA (1999)
Responsive Sequences
FK506 binding protein 1A (95 residues)