synpharm
A database of ligand-responsive protein sequences...

dasatinib

CAS Registry No. - 302962-49-8
ChEMBL Ligand - CHEMBL1421
DrugBank Ligand - DB01254
PubChem CID - 3062316
RCSB PDB Ligand - 1N1&sid=3SXR
Wikipedia - Dasatinib
PEP - dasatinib
RCSB PDB Ligand - 1N1
DrugCentral Ligand - 785
Reactome Drug - R-ALL-9669723
Reactome Reaction - R-HSA-9674430
Reactome Reaction - R-HSA-9674095
Reactome Reaction - R-HSA-9669900
Reactome Reaction - R-HSA-9669855
Reactome Reaction - R-HSA-9669854
Structure
Molecular Details
Molecular mass (Da) 487.15573
Hydrogen bond acceptors 9
Hydrogen bond donors 3
Polar surface area (A2) 134.75
Lipinski rules broken 0
logP 2.22
Other Details
Ligand type Synthetic organic
Radiolabelled No
Approved Yes
Approval Source FDA and EMA (2006)
Responsive Sequences
ABL proto-oncogene 1, non-receptor tyrosine kinase (133 residues)