CAS Registry No. - 477600-75-2
ChEMBL Ligand - CHEMBL221959
PEP - tofacitinib
PubChem CID - 9926791
RCSB PDB Ligand - MI1
Wikipedia - Tofacitinib
tofacitinib
Structure
Molecular Details
| Molecular mass (Da) | 312.16986 |
| Hydrogen bond acceptors | 7 |
| Hydrogen bond donors | 1 |
| Polar surface area (A2) | 88.91 |
| Lipinski rules broken | 0 |
| logP | 0.305 |
Other Details
| Ligand type | Synthetic organic |
| Radiolabelled | No |
| Approved | Yes |
| Approval Source | FDA (2012), EMA (2017) |
Responsive Sequences